Datasheets for both Fortekor Flavour and Benazecare state that they should be prescribed for dogs with CHF at a dose range 0.25-0.5mg benazepril hydrochloride/kg body weight once daily. And that ‘the dose may be doubled, still administered once daily, to a minimum dose of 0.5 mg/kg (range 0.5-1.0), if judged clinically necessary and advised … Continue reading
J Vet Intern Med . 2021 Jul;35(4):1673-1687Clinical efficacy of a benazepril and spironolactone combination in dogs with congestive heart failure due to myxomatous mitral valve disease: The BEnazepril Spironolactone STudy (BESST)Melissa Coffman, Emilie Guillot, Thomas Blondel, Catherine Garelli-Paar, Shuo Feng , Susanne Heartsill , Clarke E Atkins https://onlinelibrary.wiley.com/doi/full/10.1111/jvim.16155 Prepare to be confronted with a renewed … Continue reading
It pays to keep this situation under constant review. The more evidence emerges, the more there is to think about. The ACE inhibitor evidence in summary: IMPROVE study (1995): short term effects of enalapril over 21 days in heterogeneous group of dogs with CHF; conclusions rely quite heavily on subjective criteria. More benefit in DCM … Continue reading
A couple of years ago it seemed we were all more or less clear on this but, somehow, the more studies we have the muddier the waters are getting (sigh). If you want the concise version of where we are now, in my interpretation, then this is it: heart disease stage evidence-based treatment A no … Continue reading
